Rare Hematology News

Spotlight On

CAR-T therapy

Chimeric antigen receptor (CAR) T cell therapy is a type of cellular immunotherapy that changes T cells so they are able to recognize and attack cancer

5 Facts you should know

FACT

1

Chimeric antigen receptor (CAR) T-cell therapy is a technology that can genetically engineer immune cells T cells for use in immunotherapy

FACT

2

Chimeric antigen receptors are receptor proteins that have been engineered to give T cells the new ability to target a specific protein

FACT

3

The receptors are chimeric because they combine both antigen-binding and T cell activating functions into a single receptor

FACT

4

The CAR T-cell therapies approved by FDA to date target one of two antigens on B cells, CD19 or BCM

FACT

5

All currently available CAR T-cell therapies are allogeneic – and customized for each individual patient

CAR-T therapy is also known as...

CAR-T therapy

CAR-T cell therapy

Chimeric antigen receptor T cell 

CAR-T gene therapy

What’s your Rare IQ?

What’s the most commonly seen serious side effect with CAR-T cell therapy?