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Disease Profile

Double inferior vena cava

Prevalence
Prevalence estimates on Rare Medical Network websites are calculated based on data available from numerous sources, including US and European government statistics, the NIH, Orphanet, and published epidemiologic studies. Rare disease population data is recognized to be highly variable, and based on a wide variety of source data and methodologies, so the prevalence data on this site should be assumed to be estimated and cannot be considered to be absolutely correct.

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Age of onset

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ICD-10

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Inheritance

Autosomal dominant A pathogenic variant in only one gene copy in each cell is sufficient to cause an autosomal dominant disease.

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Autosomal recessive Pathogenic variants in both copies of each gene of the chromosome are needed to cause an autosomal recessive disease and observe the mutant phenotype.

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X-linked
dominant X-linked dominant inheritance, sometimes referred to as X-linked dominance, is a mode of genetic inheritance by which a dominant gene is carried on the X chromosome.

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X-linked
recessive Pathogenic variants in both copies of a gene on the X chromosome cause an X-linked recessive disorder.

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Mitochondrial or multigenic Mitochondrial genetic disorders can be caused by changes (mutations) in either the mitochondrial DNA or nuclear DNA that lead to dysfunction of the mitochondria and inadequate production of energy.

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Multigenic or multifactor Inheritance involving many factors, of which at least one is genetic but none is of overwhelming importance, as in the causation of a disease by multiple genetic and environmental factors.

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Not applicable

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Other names (AKA)

Double IVC

Categories

Congenital and Genetic Diseases

Summary

Double inferior vena cava is a vein abnormality that is present from birth (congenital). Individuals with this anomaly have two inferior vena cavas instead of one. The inferior vena cava carries oxygen-poor blood from the lower parts of the body into the heart. Double inferior vena cava does not cause any symptoms. It is usually diagnosed when an imaging test, such as CT or MRI, is performed for other medical reasons. The reported incidence of double inferior vena cava ranges from 0.2 percent to 3 percent.[1][2]

Treatment

Double inferior vena cava does not have a specified treatment, as this condition does not cause any clinical symptoms. Individuals with a double inferior vena cava who need surgery for other medical reasons may be treated more cautiously or in a different manner to prevent injury to the additional inferior vena cava.[1] Treatment may also differ for people who develop a blood clot and need an inferior vena cava filter to prevent a pulmonary embolism.[3] In these cases, a person with double inferior vena cava usually requires the placement of two filters, one in each vein.[1][2]

Learn more

These resources provide more information about this condition or associated symptoms. The in-depth resources contain medical and scientific language that may be hard to understand. You may want to review these resources with a medical professional.

In-Depth Information

  • PubMed is a searchable database of medical literature and lists journal articles that discuss Double inferior vena cava. Click on the link to view a sample search on this topic.

References

  1. Ng WT, Ng SS. Double inferior vena cava: a report of three cases. Singapore Medical Journal. June 2009; 50(6):e211-213. https://www.ncbi.nlm.nih.gov/pubmed/19551299.
  2. Shammas NW, Rachwan RJ, Daher G, Bou Dargham B. Double Inferior Vena Cava and its Implications During Endovascular and Surgical Interventions: A Word of Caution. J Invasive Cardiology. February 2017; 29(2):51-53. https://www.ncbi.nlm.nih.gov/pubmed/28145872.
  3. Mano A, Tatsumi T, Sakai H, Imoto Y, Nomura T, Nishikawa S, Takeda M, Kobara M, Yamagami T, Matsubara H. A case of deep venous thrombosis with a double inferior vena cava effectively treated by suprarenal filter implantation. Japanese Heart Journal. November 2004; 45:1063-1069. https://www.ncbi.nlm.nih.gov/pubmed/15655283.

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